Contemporary Clinical Dentistry
   
  Home | About us | Editorial board | Search
Ahead of print | Current Issue | Archives | Advertise
Instructions | Online submission| Contact us | Subscribe |

 

Login  | Users Online: 1208  Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size 

ORIGINAL ARTICLE
Year : 2021  |  Volume : 12  |  Issue : 2  |  Page : 121-127

Oral microbial shift following 1-month supplementation of probiotic chewable tablets containing Lactobacillus reuteri UBLRu-87 as an adjunct to phase 1 periodontal therapy in chronic periodontitis patients: A randomized controlled clinical trial


Department of Periodontics, Vydehi Institute of Dental Sciences and Research Centre, Rajiv Gandhi University of Health Sciences, Bengaluru, Karnataka, India

Correspondence Address:
Dr. K J Nisha
Department of Periodontics, Vydehi Institute of Dental Sciences and Research Centre, #82, EPIP Area, Nallurahalli, Whitefield, Bengaluru - 560 066, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ccd.ccd_135_20

Rights and Permissions

Context: Although Lactobacilli as a probiotic was established as a treatment for a wide range of systemic infections, its role in periodontitis and oral microbiota is still under investigation. Aims: The present randomized clinical trial was aimed to evaluate the effects of probiotic chewable tablets containing Lactobacillus reuteri UBLRu-87 along with initial periodontal therapy on clinical parameters and oral microbiota of chronic periodontitis (CP) patients. Settings and Design: The randomized controlled clinical trial. Subjects and Methods: Thirty CP patients were selected who received scaling and root planing (SRP) and were randomly allocated into two treatment groups; Groups A and B. Group A received L. reuteri-containing chewable probiotic tablets. The clinical parameters (plaque index, gingival index, probing pocket depth, clinical attachment level), and microbiological parameters (Porphyromonas gingivalis and L. reuteri levels using real-time polymerase chain reaction) were evaluated at baseline, following treatment at 1 month and 3 months in both groups. Statistical Analysis: Paired t-test and unpaired t-test were used for the statistical analysis. Results: On intergroup analysis, statistically significant improvement in clinical as well as microbiological parameters was observed in Group A (SRP + PROBIOTIC) compared to Group B (SRP ALONE) at all evaluation time points. Conclusion: Probiotic chewable tablets containing L. reuteri may be a useful adjunct along with initial periodontal therapy to slow recolonization of periopathogens along with improvement in clinical outcomes of CP. Further long-term trials are necessary to establish the optimal dosage of probiotics.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed605    
    Printed6    
    Emailed0    
    PDF Downloaded193    
    Comments [Add]    

Recommend this journal