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Year : 2013  |  Volume : 4  |  Issue : 1  |  Page : 119-123

Cowden syndrome- Clinico-radiological illustration of a rare case

Department of Oral Medicine and Radiology, Subharti Dental College, Meerut, Uttar Pradesh, India

Correspondence Address:
Prashant B Patil
Department of Oral Medicine and Radiology, Subharti Dental College, Swami Vivekanand Subharti University, Meerut 250 001, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-237X.111634

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Cowden syndrome (CS) or multiple hamartoma syndrome is an infrequent genodermatoses, which is inherited as an autosomal dominant trait resulting from the mutation in the Phosphatase and Tensin homolog gene on the arm 10q and is principally characterized by multiple hamartomas with an increased risk of development of malignancies. Facial and oral signs are remarkable in the form of multiple papules and trichilemmomas on the face. We report one such rare case of CS in a 19-year-old patient who was diagnosed on the basis of her oral mucosal lesions and was further investigated and diagnosed with other hamartomas. The present case report signifies the responsibility of the oral physician in the early diagnosis of this progressive pathological syndrome as it leaves its footmark in the oral cavity in the form of oral mucosal lesions.

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