Contemporary Clinical Dentistry

REVIEW ARTICLE
Year
: 2020  |  Volume : 11  |  Issue : 1  |  Page : 3--9

Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis


PK Sasikumar1, Sheeja S Varghese2, Thanga Kumaran3, Sakthi Saranya Devi4 
1 Department of Periodontics, JKKN Dental College, Namakkal, Tamil Nadu, India
2 Department of Periodontics, Saveetha Dental College, Chennai, Tamil Nadu, India
3 Department of Periodontics, JKKNDCH, Thiruchengodu, Tamil Nadu, India
4 Department of Oral Medicine Andradiology, KSR Institute of Dental Science and Research, Thiruchengodu, Tamil Nadu, India

Correspondence Address:
Dr. P K Sasikumar
Department of Periodontics, JKKN Dental College and Hospital, Namakkal - 638 183, Tamil Nadu
India

The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis.


How to cite this article:
Sasikumar P K, Varghese SS, Kumaran T, Devi SS. Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis.Contemp Clin Dent 2020;11:3-9


How to cite this URL:
Sasikumar P K, Varghese SS, Kumaran T, Devi SS. Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis. Contemp Clin Dent [serial online] 2020 [cited 2020 Aug 10 ];11:3-9
Available from: http://www.contempclindent.org/article.asp?issn=0976-237X;year=2020;volume=11;issue=1;spage=3;epage=9;aulast=Sasikumar;type=0