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Year : 2015  |  Volume : 6  |  Issue : 4  |  Page : 559-563

Clinical enigma: A rare case of clear cell odontogenic carcinoma

1 Department of Oral and Maxillofacial Pathology, Buraydah Private Dental College, Buraydah 31717, Saudi Arabia
2 Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India
3 Department of Orthodontics, Buraydah Private Dental College, Buraydah 31717, Saudi Arabia

Correspondence Address:
Cheshta Walia
Department of Oral and Maxillofacial Pathology, Buraidah Private Dental College, Buraidah 31717
Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-237X.169849

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Clear cell odontogenic carcinoma is a rare, aggressive neoplasm of the jaw with only 74 reported cases. It occurs predominantly in the mandibular anterior region during fifth to seventh decades of life. Clinically it manifests as intra-bony swelling with a variable degree of pain. Microscopically, it reveals nests of cells with clear cytoplasm in connective tissue stroma arranged in different patterns. It is often misdiagnosed due to the rarity of lesion and confusing histopathology. Immunohistochemical staining plays an intricate role to uncertain the native of the clear cell to reach a confirmative diagnosis. The article aims to highlight the clinicopathologic features of clear cell odontogenic carcinoma in a middle-aged man with special emphasis on its differential diagnosis.

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