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ORIGINAL ARTICLE
Year : 2012  |  Volume : 3  |  Issue : 3  |  Page : 288-293

Evaluation of minimum inhibitory and minimum bactericidal concentration of nano-silver base inorganic anti-microbial agent (Novaron® ) against streptococcus mutans


Department of Pedodontics and Preventive Dentistry, Kanti Devi Denta College and Hospital, Mathura, Uttar Pradesh, India

Correspondence Address:
Ramakrishna Yeluri
Department of Pedodontics and Preventive Dentistry, Kanti Devi Dental College and Hospital, Mathura, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-237X.103620

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Objective: We attempted to find the possibility of determining the minimum inhibitory concentration and minimum bactericidal concentration needed for nano-silver base inorganic anti-microbial agent (Novaron® AG 300, AG 1100) against Streptococcus mutans in vitro using broth dilution assay. Materials and Methods: An ampoule of freeze-dried S. mutans NCTC reference strain was revived, and the colony-forming units (CFU) were calculated. The MIC and MBC was determined by broth dilution assay using different concentrations of Novaron® AG 300 and Novaron® AG 1100 against 1 x 10 5 CFU/ml of S. mutans. Results: The MIC and MBC of Novaron® AG 300 and Novaron® AG 1100 against S. mutans were found to be 40 μg/ml. Conclusions: Novaron® has anti-bacterial effect against S. mutans. Further studies are needed to explore the applicability of these silver-supported anti- microbial agents in clinical dentistry.


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