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ORIGINAL ARTICLE
Year : 2011  |  Volume : 2  |  Issue : 4  |  Page : 274-277

Inflammatory myofibroblastic tumor


Department of Oral Pathology, Sinhgad Dental College and Hospital, Pune, Maharashtra, India

Correspondence Address:
Sangeeta Palaskar
Department of Oral Pathology, Sinhgad Dental College and Hospital, Pune - 411 041
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-237X.91787

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Inflammatory myofibroblastic tumor is an uncommon lesion of unknown cause. It encompasses a spectrum of myofibroblastic proliferation along with varying amount of inflammatory infiltrate. A number of terms have been applied to the lesion, namely, inflammatory pseudotumor, fibrous xanthoma, plasma cell granuloma, pseudosarcoma, lymphoid hamartoma, myxoid hamartoma, inflammatory myofibrohistiocytic proliferation, benign myofibroblatoma, and most recently, inflammatory myofibroblastic tumor. The diverse nomenclature is mostly descriptive and reflects the uncertainty regarding true biologic nature of these lesions. Recently, the concept of this lesion being reactive has been challenged based on the clinical demonstration of recurrences and metastasis and cytogenetic evidence of acquired clonal chromosomal abnormalities. We hereby report a case of inflammatory pseudotumor and review its inflammatory versus neoplastic behavior.


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